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Nirmatrelvir
Price range: 85 CAD through 2,384 CAD
Products Details
Product Description
– PF-07321332 is a potent and orally active inhibitor of SARS-CoV 3C-like protease (3CLPRO) .
Web ID
– T9351
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C23H32F3N5O4
Citations
– 1. Yan H, Zhang R, Yan G, et al. Production of a versatile SARS‐CoV‐2 main protease biosensor based on a dimerization‐dependent red fluorescent protein. Journal of Medical Virology. 2022
2. Yan H, Liu Z, Yan G, et al. A robust high-throughput fluorescence polarization assay for rapid screening of SARS-CoV-2 papain-like protease inhibitors. Virology. 2022
3. Yan H, Zhang R, Yan G, et al.Validation of baicalein and oridonin as nonspecific SARS‐CoV‐2 main protease inhibitors.Phytotherapy Research.2023
4. Wang Z, Pan Q, Ma L, et al.Anthracyclines inhibit SARS-CoV-2 infection.bioRxiv.2023: 2023.01. 10.523518.
5. Zhang R, Zhou J, Yan H, et al.Manidipine is not a potential inhibitor against SARS-CoV-2 main protease.Antimicrobial Agents and Chemotherapy.2024: e01297-23.
6. Mohd Abd Razak M R, Md Jelas N H, Norahmad N A, et al.In vitro study on efficacy of SKF7®, a Malaysian medicinal plant product against SARS-CoV-2.BMC Complementary Medicine and Therapies.2024, 24(1): 1-13.
7. Ye J, Xu T, Zhang R, et al.Invalidating betulinic acid as a potential inhibitor against the main protease of SARS-CoV-2 via combined approaches.Steroids.2024: 109522.
References
– Li J, et al. Nirmatrelvir exerts distinct antiviral potency against different human coronaviruses. Antiviral Res. 2023 Mar;211:105555.
CAS Number
– 2628280-40-8
Molecular Weight
– C23H32F3N5O4
Compound Purity
– 0.9993
SMILES
– C(N[C@@H](C[C@H]1C(=O)NCC1)C#N)(=O)[C@@H]2[C@@]3([C@@](C3(C)C)(CN2C([C@@H](NC(C(F)(F)F)=O)[C@](C)(C)C)=O)[H])[H]
Pathway
– Microbiology/Virology
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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