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Nimodipine-d7
$303
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Products Details
Product Description
– Nimodipine-d7 is the deuterium labeled Nimodipine. Nimodipine (BAY-e 9736) is an orally active, well-tolerated and light-sensitive dihydropyridine calcium antagonist. Nimodipine can be used for the research of cerebrovascular disorders[1].
Web ID
– HY-B0265S
Shipping
– Room temperature
Molecular Formula
– C21H19D7N2O7
References
– [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Langley, M.S., et al. Nimodipine. Drugs 37, 669–699 (1989).|[3] Marbacher S, et al. Prevention of delayed cerebral vasospasm by continuous intrathecal infusion of glyceroltrinitrate and nimodipine in the rabbit model in vivo. Intensive Care Med. 2008;34(5):932-938.|[4]Honn KV, et al. Inhibition of tumor cell-platelet interactions and tumor metastasis by the calcium channel blocker, nimodipine. Clin Exp Metastasis. 1984;2(1):61-72.
CAS Number
– 1246815-36-0
Molecular Weight
– 425.48
SMILES
– COCCOC(C1=C(C)NC(C)=C(C(OC(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H])=O)C1C2=CC(N(=O)=O)=CC=C2)=O
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease; Cancer
Solubility
– 10 mM in DMSO
Target
– Autophagy;Calcium Channel;Isotope-Labeled Compounds
Pathway
– Autophagy;Membrane Transporter/Ion Channel;Neuronal Signaling;Others
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
