NH-3
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NH-3

SKU T40548-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 366 CAD through 7,392 CAD

Products Details

Product Description

– NH-3 is a potent orally active thyroid hormone receptor (THR) antagonist which exhibits reversible behavior, demonstrated by an IC 50 of 55 nM. Derived from the selective thyromi-metic GC-1, NH-3 effectively inhibits the binding of thyroid hormones to their respective receptors, resulting in hindered cofactor recruitment.

Web ID

– T40548

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C28H27NO6

References

– Latika Singh, et al. Chasing the Elusive Benzofuran Impurity of the THR Antagonist NH-3: Synthesis, Isotope Labeling, and Biological Activity. J Org Chem. 2016 Mar 4;81(5):1870-6.

CAS Number

– 447415-26-1

Molecular Weight

– C28H27NO6

Compound Purity

– 0.994

SMILES

– CC(C)c1cc(Cc2c(C)cc(OCC(O)=O)cc2C)cc(C#Cc2ccc(cc2)[N+]([O-])=O)c1O

Pathway

– Endocrinology/Hormones

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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