Nemiralisib
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Nemiralisib

SKU T15431-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 64 CAD through 762 CAD

Products Details

Product Description

– Nemiralisib(GSK-2269557 free base) is an orally available, potent and specific PI3Kδ inhibitor with a pKi of 9.9.Nemiralisib is used for the treatment of respiratory diseases including chronic obstructive pulmonary disease.

Web ID

– T15431

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C26H28N6O

References

– Down K et al. Optimization of Novel Indazoles as Highly Potent and Selective Inhibitors of Phosphoinositide 3-Kinase δ for the Treatment of Respiratory Disease. J Med Chem. 2015 Sep 24;58(18):7381-99.

CAS Number

– 1254036-71-9

Molecular Weight

– C26H28N6O

Compound Purity

– 0.9991

SMILES

– CC(C)N1CCN(Cc2cnc(o2)-c2cc(cc3[nH]ncc23)-c2cccc3[nH]ccc23)CC1

Pathway

– PI3K/Akt/mTOR signaling

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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