NecroX-7
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NecroX-7

SKU T9948-1 mg Category Brand:

Price range: 82 CAD through 317 CAD

Products Details

Product Description

– NecroX-7 (LC-280126) is a potent free radical scavenger and HMGB1 (high-mobility group box 1) inhibitor. It serves as an antidote to acetaminophen toxicity and exerts a protective effect by preventing HMGB1 release in ischemia/reperfusion injury. Additionally, NecroX-7 inhibits HMGB1-induced release of TNF and IL-6 and the expression of TLR-4 and receptor for advanced glycation end products. This compound may be used for graft-versus-host disease (GVHD) research [1].

Web ID

– T9948

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C24H29N3O3S

References

– Grootaert MOJ, et al. NecroX-7 reduces necrotic core formation in atherosclerotic plaques of Apoe knockout mice. Atherosclerosis. 2016 Sep;252:166-174.

CAS Number

– 1120332-55-9

Molecular Weight

– C24H29N3O3S

Compound Purity

– 0.9808

SMILES

– N(C1=C2C(C=C(N2)C3=CC=CC=C3)=CC(CN4CCS(=O)(=O)CC4)=C1)C5CCOCC5

Pathway

– Immunology/Inflammation

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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