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Products Details
Product Description
– Nav1.3 channel inhibitor 1 (compound 15b) is a state-dependent voltage-gated sodium channel Nav1.3 inhibitor (IC50=20 nM). Nav1.3 channel inhibitor 1 can penetrate the blood-brain barrier and can be used in the research of nervous system diseases[1].
Web ID
– HY-155058
Shipping
– Room temperature
Molecular Formula
– C19H15F2N3O3S2
References
– [1]Zidar N, et al. New aryl and acylsulfonamides as state-dependent inhibitors of Nav1.3 voltage-gated sodium channel. Eur J Med Chem. 2023 Oct 5;258:115530.
Molecular Weight
– 435.47
SMILES
– O=C(C1C(C2=CC=C(F)C(F)=C2)C1)NC3=CC=C(S(=O)(NC4=NC=CS4)=O)C=C3
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Sodium Channel
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
