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Products Details
Product Description
– NaV1.2/1.6 channel blocker-1 is a potent NaV1.2/1.6 channel blocker, with IC50s of 9.8 and 24.4 μM for rNaV1.6 and hNaV1.2, respectively. NaV1.2/1.6 channel blocker-1 can be used for the research of generalized epilepsy[1].
Web ID
– HY-152166
Shipping
– Room temperature
Molecular Formula
– C14H14N2OS
References
– [1]Rivara M, et, al. Biological Evaluation of Imidazobenzoxazines, Imidazobenzoxazin-5-ones and Imidazobenzoxazin-5-thiones as Sodium Channel Blockers. Letters in Drug Design & Discovery, 2014, 11, 90-97.
CAS Number
– 1199944-04-1
Molecular Weight
– 258.34
SMILES
– S=C1OC2=CC=CC=C2C3=NC(C)=C(CCC)N13
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Sodium Channel
Isoform
– Nav1.2;Nav1.6
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
