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Products Details
Product Description
– Nampt-IN-7 (compound GF8) is a potent NAMPT inhibitor, with an IC50 of 7.31 μM. Nampt-IN-7 also displays cytotoxic activity against human HepG2 hepatocellular carcinoma cell line with an IC50 of 24.28 μM[1].
Web ID
– HY-147756
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C20H21N5O3
References
– [1]Ozgencil F, et al. Identification of small-molecule urea derivatives as novel NAMPT inhibitors via pharmacophore-based virtual screening. Bioorg Med Chem. 2020 Jan 1;28(1):115217.
CAS Number
– 1223378-42-4
Molecular Weight
– 379.41
SMILES
– CCOC(C1=CC=C(C=C1)NC(NCC2=CC(N3C=CN=C3C)=NC=C2)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– NAMPT
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
