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Products Details
Product Description
– N-type calcium channel blocker-1 is an orally active compound which shows high affinity to functionally block N-type calcium channels with an IC50 of 0.7 μM in the IMR32 assay.
Web ID
– HY-100310
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C31H47N3
References
– [1]Hu LY, et al. The discovery of [1-(4-dimethylamino-benzyl)-piperidin-4-yl]-[4-(3,3-dimethylbutyl)-phen yl]-(3-methyl-but-2-enyl)-amine, an N-type Ca+2 channel blocker with oral activity for analgesia. Bioorg Med Chem. 2000 Jun;8(6):1203-12.
CAS Number
– 241499-17-2
Molecular Weight
– 461.73
SMILES
– C/C(C)=CCN(C1=CC=C(CCC(C)(C)C)C=C1)C2CCN(CC3=CC=C(N(C)C)C=C3)CC2
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Calcium Channel
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
