N-Ethylmaleimide
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N-Ethylmaleimide

SKU T3088-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 62 CAD through 378 CAD

Products Details

Product Description

– N-Ethylmaleimide (NEM) is a reagent for alkylation of free sulfhydryl groups, a cysteine protease inhibitor used in experimental biochemistry. N-Ethylmaleimide is also a deubiquitinating enzyme inhibitor that specifically inhibits phosphate transport in mitochondria.

Web ID

– T3088

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C6H7NO2

Citations

– 1. Hussain M, Lu Y, Tariq M, et al. A small-molecule Skp1 inhibitor elicits cell death by p53-dependent mechanism. Iscience. 2022, 25(7): 104591. 2. Ren W, Xu Z, Chang Y, et al.Pharmaceutical targeting of OTUB2 sensitizes tumors to cytotoxic T cells via degradation of PD-L1.Nature Communications.2024, 15(1): 9. 3. Shao Z, Liu S, Sun W, et al.SENP3 mediates deSUMOylation of SIX1 to promote prostate cancer proliferation and migration.Cellular & Molecular Biology Letters.2024, 29(1): 1-20. 4. Zhang X L, Yue H W, Liu Y J, et al.Designer polyQ fusion proteins sequester USP7/HDM2 for modulating P53 functionality.iScience.2025

References

– Chen YQ, et al. J Biophotonics. 2014 Aug;7(8):647-55.

CAS Number

– 128-53-0

Molecular Weight

– C6H7NO2

Compound Purity

– 0.995

SMILES

– C(C)N1C(=O)C=CC1=O

Pathway

– Cell Cycle/Checkpoint|||Ubiquitination|||Proteases/Proteasome|||DNA Damage/DNA Repair

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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