N-Desethyl Sunitinib
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N-Desethyl Sunitinib

SKU T12145-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 123 CAD through 243 CAD

Products Details

Product Description

– N-Desethyl Sunitinib (SU012662) is the primary active metabolite of Sunitinib produced by the metabolism of cytochrome P450 enzyme 3A4 (CYP3A4).Sunitinib is an orally available inhibitor of a number of tyrosine kinases involved in tumor proliferation and angiogenesis, including VEGFR, PDGFR, KIT, and FLT3, and was approved for the treatment of advanced/metastatic renal cell carcinoma (RCC)

Web ID

– T12145

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H23FN4O2

References

– O’Farrell AM, et al. SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo. Blood. 2003 May 1;101(9):3597-605. Epub 2003 Jan 16.

CAS Number

– 356068-97-8

Molecular Weight

– C20H23FN4O2

SMILES

– C(=C1/C=2C(NC1=O)=CC=C(F)C2)C3=C(C)C(C(NCCNCC)=O)=C(C)N3

Target

– Others

Pathway

– Metabolism|||Tyrosine Kinase/Adaptors|||Angiogenesis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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