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N-Demethyl MK-6884
SKU
HY-150018-10 mg
Category Reference compound
Tags GPCR/G Protein;Neuronal Signaling, mAChR, Neurological Disease
$500 – $850
Products Details
Product Description
– N-Demethyl MK-6884 (compound 34) is a potent M4 mAChR allosteric modulator. N-Demethyl MK-6884 can be used in the studies of alzheimer’s disease and other diseases mediated by the M4 mAChR[1].
Web ID
– HY-150018
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C24H23N5O
References
– [1]John J. Acton, et al. 3- (1h-pyrazol-4-yl) pyridineallosteric modulators of the m4 muscarinic acetylcholine receptor. Patent WO2017107089A1.
CAS Number
– 2102194-36-3
Molecular Weight
– 397.47
Compound Purity
– 99.21
SMILES
– N#CC1=CC=C(C2=CN(CC3(CCCC3)C)N=C2)C(C4=CC(C(NC5)=O)=C5C=C4)=N1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 31.25 mg/mL (ultrasonic)
Target
– mAChR
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.