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N-(5-Hydroxypentyl)maleimide
$350 – $950
Products Details
Product Description
– N-(5-Hydroxypentyl)maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as Gemcitabine-O-Si(di-iso)-O-Mc (HY-130812) )[1].
Web ID
– HY-130818
Storage Temperature
– -20°C (Powder, stored under nitrogen)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C9H13NO3
References
– [1] Finniss, M. C., et al. A versatile acid-labile linker for antibody–drug conjugates. Med. Chem. Commun., 2014, 5(9), 1355-1358.
CAS Number
– 180608-78-0
Molecular Weight
– 183.20
Compound Purity
– 99.89
SMILES
– OCCCCCN1C(C=CC1=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ADC Linker
Isoform
– Non-cleavable Linker
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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