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Nω-Propyl-L-arginine (hydrochloride)
SKU
HY-102062A-10 mg
Category Reference compound
Tags Immunology/Inflammation, Neurological Disease, NO Synthase
$120 – $620
Products Details
Product Description
– Nω-Propyl-L-arginine (N-omega-Propyl-L-arginine) hydrochloride is a potent, competitive, and highly selective inhibitor of neuronal nitric oxide synthase (nNOS), with a Ki of 57 nM. Nω-Propyl-L-arginine hydrochloride displays a 149-fold selectivity for nNOS over endothelial NOS (eNOS)[1][2].
Web ID
– HY-102062A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C9H21ClN4O2
References
– [1]Zhang HQ, et al. Potent and selective inhibition of neuronal nitric oxide synthase by N omega-propyl-L-arginine. J Med Chem. 1997 Nov 21;40(24):3869-70.|[2]Klamer D, et al. The neuronal selective nitric oxide synthase inhibitor, Nomega-propyl-L-arginine, blocks the effects of phencyclidine on prepulse inhibition and locomotor activity in mice. Eur J Pharmacol. 2004 Oct 25;503(1-3):103-7.
CAS Number
– 2321366-46-3
Molecular Weight
– 252.74
Compound Purity
– 98.0
SMILES
– N[C@@H](CCCNC(NCCC)=N)C(O)=O.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– H2O : 25 mg/mL (ultrasonic;warming)|DMSO : 25 mg/mL (ultrasonic;warming)
Target
– NO Synthase
Isoform
– nNOS
Pathway
– Immunology/Inflammation
Product type
– Reference compound
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