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Products Details
Product Description
– Mu opioid receptor antagonist 7 (compound 24) is a potent and CNS permeable antagonist of µOR (µ-opioid receptor), with an IC50 of 29 ± 3.0 nM. Mu opioid receptor antagonist 7 can be used for the research of pain and opioid use disorder[1].
Web ID
– HY-155320
Shipping
– Room temperature
Molecular Formula
– C22H27ClN2O2
References
– [1]Nerurkar A, et al. Novel series of tunable µOR modulators with enhanced brain penetration for the treatment of opioid use disorder, pain and neuropsychiatric indications. Bioorg Med Chem Lett. 2023 Aug 15;92:129405.
CAS Number
– 2378397-30-7
Molecular Weight
– 386.91
SMILES
– OC1=CC(Cl)=C(C[C@H](N(C)C)CNC([C@@H]2C[C@]2(C)C3=CC=CC=C3)=O)C=C1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Opioid Receptor
Isoform
– μ Opioid Receptor/MOR
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
