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MS-444
$300 – $6,200
Products Details
Product Description
– MS-444 inhibits the activity of purified smooth muscle myosin light chain kinase (MLCK) with an IC50 value of 10 μM.
Web ID
– HY-100685
Storage Temperature
– -20°C (Powder, protect from light, stored under nitrogen)
Shipping
– Blue Ice
Applications
– Cancer-Kinase/protease
Molecular Formula
– C13H10O4
References
– [1]Satoshi Nakanishi. et al. MS-444, a new inhibitor of myosin light chain kinase from <i>Micromonosporasp</i>.KY7123. The Journal Of Antibiotics. 1995,48(9):948-951.|[2]Fernando F. Blanco.et al, Impact of HuR inhibition by the small molecule MS-444 on colorectal cancer cell tumorigenesis. Oncotarget. 2016 Nov 8; 7(45): 74043-74058.
CAS Number
– 150045-18-4
Molecular Weight
– 230.22
Compound Purity
– 99.42
SMILES
– O=C(C1=C(C)OC=C1C2)C3=C2C(O)=CC=C3O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 1-Methyl-2-pyrrolidinone : ≥ 20 mg/mL|DMSO : 50 mg/mL (ultrasonic)
Target
– Myosin
Pathway
– Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
