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MRGPRX1 agonist 1
$350 – $2,500
Products Details
Product Description
– MRGPRX1 agonist 1 is a highly potent agonist of MRGPRX1 (Mas-related G-protein-coupled receptor X1), with an EC50 of 50 nM, and is inactive on MRGPRC11. Analgesic effect[1].
Web ID
– HY-130118
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C23H21N3O4S
References
– [1]Prchalová E, et al. Discovery of Benzamidine- and 1-Aminoisoquinoline-Based Human MAS-Related G-Protein-Coupled Receptor X1 (MRGPRX1) Agonists. J Med Chem. 2019 Sep 26;62(18):8631-8641.
CAS Number
– 2377379-39-8
Molecular Weight
– 435.50
Compound Purity
– 99.97
SMILES
– O=S(C1=CC=CC=C1OC)(NC2=CC=C(C)C=C2OC3=CC4=C(C(N)=NC=C4)C=C3)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 125 mg/mL (ultrasonic)
Target
– Mas-related G-protein-coupled Receptor (MRGPR)
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
