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Products Details
Product Description
– MptpB-IN-1 (Compound 13) is a potent and orally active inhibitor of MptpB. Mycobacterium tuberculosis protein-tyrosine-phosphatase B (MptpB) is a secreted virulence factor that subverts antimicrobial activity in the host. MptpB-IN-1 reduces multidrug-resistant mycobacterium tuberculosis survival and infection burden[1].
Web ID
– HY-145741
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C17H11Cl2NO4
References
– [1]Vickers CF, et al. Structure-Based Design of MptpB Inhibitors That Reduce Multidrug-Resistant Mycobacterium tuberculosis Survival and Infection Burden in Vivo. J Med Chem. 2018;61(18):8337-8352.
CAS Number
– 2244622-44-2
Molecular Weight
– 364.18
SMILES
– O=C(C1=NOC(C)=C1C2=CC=CC(C3=CC(Cl)=C(C(Cl)=C3)O)=C2)O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Antibiotic
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
