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Products Details
Product Description
– mp-dLAE-PABC-MMAE is a agent-linker conjugate for ADC. mp-dLAE-PABC-MMAE contains a potent tubulin inhibitor Monomethyl auristatin E (HY-15162). mp-dLAE-PABC-MMAE can be used to synthesis antibody-drug conjugates (ADCs)[1].
Web ID
– HY-152916
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C68H102N10O17
References
– [1]Sandall Sharsti and Waight Andrew. Engineering of anti-CD228 antibodies and antibody-drug conjugates for cancer immunotherapy. WO2022031652. 2022.
CAS Number
– 2625616-44-4
Molecular Weight
– 1331.59
SMILES
– O=C(N(C)[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N([C@H]([C@@H](CC(N1[C@H]([C@H](OC)[C@H](C(N[C@@H]([C@@H](O)C2=CC=CC=C2)C)=O)C)CCC1)=O)OC)[C@@H](C)CC)C)=O)=O)OCC3=CC=C(NC([C@H](CCC(O)=O)NC([C@H](C)NC([C@@H](CC(C)C)NC(CCN4C(C=CC4=O)=O)=O)=O)=O)=O)C=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Drug-Linker Conjugates for ADC
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
