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Products Details
Product Description
– Mosapride-d5 is the deuterium labeled Mosapride. Mosapride is a gastroprokinetic agent that acts as a selective 5HT4 agonist.
Web ID
– HY-B0189S1
Shipping
– Room temperature
Molecular Formula
– C21H20D5ClFN3O3
References
– [1]Tack J, et al. Systematic review: cardiovascular safety profile of 5-HT(4) agonists developed for gastrointestinal disorders. Aliment Pharmacol Ther. 2012 Apr;35(7):745-67.|[2]Curran MP, et al. Mosapride in gastrointestinal disorders. Drugs. 2008;68(7):981-91.|[3]Odaka T, et al. Serotonin 5- HT4 receptor agonist (mosapride citrate). Nihon Rinsho. 2006 Aug;64(8):1491-4.|[4]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
CAS Number
– 1246820-66-5
Molecular Weight
– 426.92
SMILES
– FC(C=C1)=CC=C1CN(CCO2)CC2CNC(C3=C(C=C(C(Cl)=C3)N)OC([2H])([2H])C([2H])([2H])[2H])=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– 5-HT Receptor;Isotope-Labeled Compounds
Pathway
– GPCR/G Protein;Neuronal Signaling;Others
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
