MNK8 
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MNK8 

SKU T9945-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 54 CAD through 341 CAD

Products Details

Product Description

– MNK8 (3-methyl-6-(naphthalen-1-yl)pyrimidine-2,4(1H,3H)-dione) is a potent STAT3 inhibitor that reduces the ability of STAT3 to bind to DNA and also has a good growth inhibition effect on liver cancer cells [1].

Web ID

– T9945

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C15H12N2O2

References

– Ayyiliath M Sajith, et al. Pyrimidine-2,4-dione targets STAT3 signaling pathway to induce cytotoxicity in hepatocellular carcinoma cells. Bioorg Med Chem Lett. 2021 Oct 15;50:128332.

CAS Number

– 2055078-49-2

Molecular Weight

– C15H12N2O2

Compound Purity

– 0.9974

SMILES

– O=C1C=C(C=2C3=C(C=CC2)C=CC=C3)NC(=O)N1C

Pathway

– Stem Cells|||JAK/STAT signaling

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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