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Products Details
Product Description
– MMP2-IN-2 (compound 42) is a potent and selective inhibitor of MMP-2 (matrix metalloproteinases) with an IC50 of 4.2 μM, and it also shows inhibitory activity against MMP-13, MMP-9, and MMP-8 with IC50 values of 12, 23.3, and 25 μM, respectively [1].
Web ID
– T60551
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C13H8N4O4
References
– Laghezza A, et al. Virtual screening identification and chemical optimization of substituted 2-arylbenzimidazoles as new non-zinc-binding MMP-2 inhibitors. Bioorg Med Chem. 2020 Feb 1;28(3):115257.
CAS Number
– 1772-39-0
Molecular Weight
– C13H8N4O4
Compound Purity
– 0.9809
SMILES
– O=[N+]([O-])C1=CC=C(C2=NC3=CC=C([N+]([O-])=O)C=C3N2)C=C1
Pathway
– Proteases/Proteasome
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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