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Products Details
Product Description
– MMG-11 inhibits both TLR2/1 and TLR2/6 signaling (IC50s: 1.7 μM for Pam3CSK4-induced hTLR2/1 and 5.7 μM for Pam2CSK4-induced hTLR2/6 responses). MMG-11 is an effective and selective human TLR2 antagonist with low cytotoxicity.
Web ID
– T16123
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C15H14O7
References
– Grabowski M, et al. Identification of a pyrogallol derivative as a potent and selective human TLR2 antagonist by structure-based virtual screening. Biochem Pharmacol. 2018 Aug;154:148-160.
CAS Number
– 313254-94-3
Molecular Weight
– C15H14O7
SMILES
– CCOC(=O)c1ccc(CC(=O)c2ccc(O)c(O)c2O)o1
Target
– Cell Cycle Arrest
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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