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MLN9708 analogues

SKU T2016-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 69 CAD through 901 CAD

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Product Description

– MLN2238 suppresses the chymotrypsin-like proteolytic (β5) site of the 20S proteasome(Ki50=0.93 nM, IC50=3.4 nM/). The biologically active form of MLN9708 (Ixazomib Citrate) is MLN2238 in aqueous solutions or plasma.

Web ID

– T2016

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H23BCl2N2O9

Citations

– 1. Zhou Q, Liang J, Yang T, et al. Carfilzomib modulates tumor microenvironment to potentiate immune checkpoint therapy for cancer. EMBO Molecular Medicine. 2022 Jan 11;14(1):e14502. doi: 10.15252/emmm.202114502. Epub 2021 Dec 13.

References

– Kupperman E, et al. Cancer Res, 2010, 70(5), 1970-80.

CAS Number

– 1201902-80-8

Molecular Weight

– C20H23BCl2N2O9

Compound Purity

– 0.9923

SMILES

– CC(C)C[C@H](NC(=O)CNC(=O)c1cc(Cl)ccc1Cl)B1OC(=O)CC(CC(O)=O)(O1)C(O)=O

Target

– Others

Pathway

– Proteases/Proteasome|||Ubiquitination

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

MLN9708 analogues

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