Download Files:
ML418
$154 – $1,650
Products Details
Product Description
– ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker. ML418 inhibits Kir7.1 with an IC50 value of 0.31 μM. ML418 can be used for the research of neurological, cardiovascular, endocrine and muscle disorders.
Web ID
– HY-122697
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C19H24ClN3O3
References
– [1]ML418, et al. ML418: The First Selective, Sub-Micromolar Pore Blocker of Kir7.1 Potassium Channels. ACS Chem Neurosci. 2016 Jul 20;7(7):1013-23.
CAS Number
– 1928763-08-9
Molecular Weight
– 377.87
Compound Purity
– 99.89
SMILES
– O=C(OC(C)C)NC1CCN(CC2=CC(Cl)=C3C=CC=NC3=C2O)CC1
Clinical Information
– No Development Reported
Research Area
– Endocrinology; Neurological Disease; Cardiovascular Disease
Solubility
– DMSO : 20.83 mg/mL (ultrasonic)
Target
– Potassium Channel
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
