ML266
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ML266

SKU T8990-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 77 CAD through 2,432 CAD

Products Details

Product Description

– ML266, a glucocerebrosidase (GCase) chaperone with an IC50 of 2.5 µM, facilitates the transport of the mutant protein to the lysosome, thereby restoring GCase activity without inhibiting the enzyme’s function. This compound shows promise for Gaucher disease research.

Web ID

– T8990

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C24H22BrN3O4

References

– Rogers S, et al. Discovery, SAR, and Biological Evaluation of Non-inhibitory Chaperones of Glucocerebrosidase. 2012 Mar 27 [updated 2013 Mar 7].

CAS Number

– 1462267-08-8

Molecular Weight

– C24H22BrN3O4

Compound Purity

– 0.9845

SMILES

– CN(C(=O)CNC(=O)c1ccccc1OCC(=O)Nc1ccc(Br)cc1)c1ccccc1

Pathway

– Metabolism

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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