Download Files:
ML202
$110 – $2,800
Products Details
Product Description
– ML202 is a highly specific allosteric activator of human pyruvate kinase M2 (hPK-M2), which can affect the cooperativity of phosphoenolpyruvate (PEP) binding, while adenosine diphosphate (ADP) binding almost no effect[1].
Web ID
– HY-110124
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C18H17N3O3S2
References
– [1]Matthew B Boxer, et al. Identification of activators for the M2 isoform of human pyruvate kinase Version 3. 2009 Sep 1 [updated 2011 Mar 3]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–.Â
CAS Number
– 1221186-52-2
Molecular Weight
– 387.48
Compound Purity
– 99.27
SMILES
– O=C1C2=C(C3=C(N2C)C=C(S(C)=O)S3)C=NN1CC4=CC(OC)=CC=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 50 mg/mL (ultrasonic)
Target
– Pyruvate Kinase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
