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MK-7622
SKU
HY-15618-1 mg
Category Reference compound
Tags GPCR/G Protein;Neuronal Signaling, mAChR, Neurological Disease
$42 – $720
Products Details
Product Description
– MK-7622 (M1 receptor modulator) is a muscarinic M1 receptor positive allosteric modulator[1][2].
Web ID
– HY-15618
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C25H25N3O2
References
– [1]Kuduk Scott D, et al. Dihydrobenzoquinazolinone M1 receptor positive allosteric modulators. From PCT Int. Appl. (2012), WO 2012047702 A1 20120412.|[2]Kuduk Scott D, et al. Benzoquinazolinone derivatives as M1 receptor positive allosteric modulators and their preparation, pharmaceutical compositions and use in the treatment of diseases. From PCT Int. Appl. (2010), WO 2010059773 A1 20100527.
CAS Number
– 1227923-29-6
Molecular Weight
– 399.48
Compound Purity
– 98.98
SMILES
– O=C1N([C@@H]2[C@@H](O)CCCC2)C=NC3=C1C=C(CC4=CC=C(C)N=C4)C5=CC=CC=C53
Clinical Information
– Phase 2
Research Area
– Neurological Disease
Solubility
– DMSO : ≥ 100 mg/mL
Target
– mAChR
Isoform
– mAChR1
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.