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MK-3328
$571
Only 1000 item(s) left in stock.
Products Details
Product Description
– MK-3328 is a β-Amyloid PET ligand, which exhibits high binding potency with an IC50 of 10.5 nM[1][2].
Web ID
– HY-100275
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C14H9FN4O
References
– [1]Harrison ST, et al. Synthesis and Evaluation of 5-Fluoro-2-aryloxazolo[5,4-b]pyridines as β-Amyloid PET Ligands and Identification of MK-3328. ACS Med Chem Lett. 2011 Apr 18;2(7):498-502.|[2]Hostetler ED, et al. [18F]Fluoroazabenzoxazoles as potential amyloid plaque PET tracers: synthesis and in vivo evaluation in rhesus monkey. Nucl Med Biol. 2011 Nov;38(8):1193-203.
CAS Number
– 1201323-97-8
Molecular Weight
– 268.25
SMILES
– CN1C=CC2=CC(C3=NC4=CC=C(F)N=C4O3)=CN=C21
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Amyloid-β
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
