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MK-28
$300 – $2,100
Products Details
Product Description
– MK-28 is a potent and selective PERK activator. MK-28 exhibits remarkable pharmacokinetic properties and high BBB penetration in mice[1].
Web ID
– HY-137207
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C24H20N4O2
References
– [1]Javier Ganz, et al. A novel specific PERK activator reduces toxicity and extends survival in Huntington’s disease models. Sci Rep. 2020 Apr 23;10(1):6875.
CAS Number
– 864388-65-8
Molecular Weight
– 396.44
Compound Purity
– 99.50
SMILES
– OC1=CC=C(C=C1O)/C=N/N(C2=NC(C3=CC=CC=C3)=CC(C4=CC=CC=C4)=N2)C
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 12.5 mg/mL (ultrasonic)
Target
– PERK
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
