Mivebresib
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Mivebresib

SKU T3712-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 85 CAD through 1,112 CAD

Products Details

Product Description

– Mivebresib (ABBV-075), also known as ABBV-075, is a potent BET inhibitor (bromodomain (BRD)-containing protein) with potential antineoplastic activity. Upon administration, the bromodomain inhibitor ABBV-075 binds to the acetyl-lysine binding site in the BRD of certain BRD-containing protein(s), thereby preventing the interaction between those proteins and acetylated histones. This disrupts chromatin remodeling, prevents the expression of certain growth-promoting genes, and leads to an inhibition of cell growth in susceptible tumors. Also a potent inhibitor of MYC and the TMPRSS2-ETS fusion proteins.

Web ID

– T3712

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H19F2N3O4S

References

– Aparna Sarthy, et al. Experimental and Molecular Therapeutics. 2016, Abstract 4718.

CAS Number

– 1445993-26-9

Molecular Weight

– C22H19F2N3O4S

Compound Purity

– 0.9932

SMILES

– O(C1=C(C=2C3=C(C(=O)N(C)C2)NC=C3)C=C(NS(CC)(=O)=O)C=C1)C4=C(F)C=C(F)C=C4

Pathway

– Chromatin/Epigenetic|||Apoptosis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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