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MitoSOX Red
$62 – $340
Products Details
Product Description
– MitoSOX Red is a novel fluorescent probe that specifically targets mitochondria in living cells with cell membrane permeability. MitoSOX Red enters the mitochondria, it is oxidized by superoxide, but not by other ROS or RNS generating systems. MitoSOX Red then binds to intramitochondrial nucleic acids, producing strong red fluorescence. MitoSOX Red can be used as a fluorescent indicator to specifically detect superoxide. Additionally, Superoxide dismutase (SOD) prevents the oxidation of MitoSOX Red.Excitation/emission wavelength: 510/580 nm.
Web ID
– HY-D1055
Storage Temperature
– -20°C (Powder, protect from light, stored under nitrogen)
Shipping
– Blue Ice
Molecular Formula
– C43H43IN3P
References
– [1]Fengjiao Jin, et al. The PI3K/Akt/GSK-3β/ROS/eIF2B pathway promotes breast cancer growth and metastasis via suppression of NK cell cytotoxicity and tumor cell susceptibility. Cancer Biol Med. 2019 Feb;16(1):38-54.|[2]Price OT, et al. Quantitative fluorescence of 5-FU-treated fetal rat limbs using confocal laser scanning microscopy and Lysotracker Red. Cytometry A. 2003;53(1):9-21.|[3]Fengjiao Jin, et al. The PI3K/Akt/GSK-3β/ROS/eIF2B pathway promotes breast cancer growth and metastasis via suppression of NK cell cytotoxicity and tumor cell susceptibility. Cancer Biol Med. 2019 Feb;16(1):38-54.
CAS Number
– 1003197-00-9
Molecular Weight
– 759.70
Compound Purity
– 95.25
SMILES
– NC1=CC(C(C2=CC=CC=C2)N(CCCCCC[P+](C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)C6=CC(N)=CC=C76)=C7C=C1.[I-]
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Fluorescent Dye;Mitochondrial Metabolism;Reactive Oxygen Species
Pathway
– Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB;Others
Product type
– Dye Reagents
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
