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Miriplatin
SKU
HY-16325A-10 mg
Category Reference compound
Tags Cancer, Cell Cycle/DNA Damage, DNA Alkylator/Crosslinker
$50 – $220
Products Details
Product Description
– Miriplatin (SM-11355) is a chemotherapy agent which belongs to the class of alkylating agents.
Web ID
– HY-16325A
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C34H68N2O4Pt
References
– [1]Kishimoto S, et al. Antitumor effects of a novel lipophilic platinum complex (SM-11355) against a slowly-growing rat hepatic tumor after intra-hepatic arterial administration. Biol Pharm Bull. 2000 Mar;23(3):344-8.|[2]Hanada M, et al. Intra-hepatic arterial administration with miriplatin suspended in an oily lymphographic agent inhibits the growth of tumors implanted in rat livers by inducing platinum-DNA adducts to form and massive apoptosis. Cancer Chemother Pharmacol. 2009 Aug;64(3):473-83.
CAS Number
– 141977-79-9
Molecular Weight
– 764.00
Compound Purity
– 98.0
SMILES
– NC1CCCCC1N.[O-]C(CCCCCCCCCCCCC)=O.[O-]C(CCCCCCCCCCCCC)=O.[Pt+2]
Clinical Information
– Launched
Research Area
– Cancer
Solubility
– Acetone : 1.1 mg/mL (ultrasonic)|DMF : 1 mg/mL (ultrasonic)|H2O : 0.1 mg/mL (ultrasonic)
Target
– DNA Alkylator/Crosslinker
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
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