MID-1
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MID-1

SKU T8773-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 74 CAD through 1,245 CAD

Products Details

Product Description

– MID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction. It disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake

Web ID

– T8773

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C12H11N3O4S

References

– Lee H, et, al. MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) Interaction Disruptor Sensitizes Insulin Signaling in Skeletal Muscle. J Biol Chem. 2016 Dec 23;291(52):26627-26635.

CAS Number

– 312608-54-1

Molecular Weight

– C12H11N3O4S

Compound Purity

– 0.9939

SMILES

– CCOc1ccc(cc1)C(=O)Nc1ncc(s1)[N+]([O-])=O

Pathway

– Tyrosine Kinase/Adaptors

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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