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Micheliolide
$50 – $240
Products Details
Product Description
– Micheliolide can attenuate high glucose-stimulated NF-κB activation, IκBα degradation, and the expression of MCP-1, TGF-β1, and FN in mouse mesangial cells.
Web ID
– HY-N0847
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C15H20O3
References
– [1]Jia QQ, et al. Sesquiterpene lactones and their derivatives inhibit high glucose-induced NF-κB activation and MCP-1 and TGF-β1 expression in rat mesangial cells. Molecules. 2013 Oct 21;18(10):13061-77.
CAS Number
– 68370-47-8
Molecular Weight
– 248.32
Compound Purity
– 99.84
SMILES
– O=C(O[C@@]1([H])[C@@]2([H])CCC(C)=C3CC[C@@](C)(O)[C@@]31[H])C2=C
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– NF-κB
Pathway
– NF-κB
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.