Methylnaltrexone bromide

SKU T21422-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 75 CAD through 795 CAD

Products Details

Product Description

– Methylnaltrexone bromide (MOA-728) is one of the newer agents of peripherally-acting μ-opioid antagonists. Methylnaltrexone bromide acts to reverse some of the side effects of opioid drugs such as constipation without affecting analgesia or precipitating withdrawals.

Web ID

– T21422

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H26BrNO4

Citations

– 1. Liu X, Yang J, Yang C, et al. Morphine promotes the malignant biological behavior of non-small cell lung cancer cells through the MOR/Src/mTOR pathway. Cancer Cell International. 2021, 21(1): 1-14 2. Liu X, Yang J, Yang C, et al. Morphine promotes the malignant biological behavior of non-small cell lung cancer cells through the MOR/Src/mTOR pathway. Cancer cell International. 2021, 21(1): 1-14 3. Gu F, Zhou Y, Tian L, et al.Morphine promotes non-small cell lung cancer progression by downregulating E-cadherin via the PI3K/AKT/mTOR pathway.Scientific Reports.2024, 14(1): 21130.

References

– Rauck RL. Treatment of opioid-induced constipation: focus on the peripheral μ-opioid receptor antagonist methylnaltrexone. Drugs. 2013 Aug;73(12):1297-306. doi: 10.1007/s40265-013-0084-5. Review. PubMed PMID: 23881667.

CAS Number

– 73232-52-7

Molecular Weight

– C21H26BrNO4

Compound Purity

– 0.9988

SMILES

– O=C1[C@@](OC2=C(O)C=CC3=C24)([H])[C@@]54CC[N+](C)(CC6CC6)[C@@](C3)([H])[C@]5(O)CC1.[Br-]

Pathway

– GPCR/G Protein|||Neuroscience|||Endocrinology/Hormones

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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