Metformin-d6 (hydrochloride)

$115$400

Products Details

Product Description

– Metformin-d6 (hydrochloride)e is a deuterium labeled Metformin hydrochloride. Metformin hydrochloride inhibits the mitochondrial respiratory chain in the liver, leading to activation of AMPK, enhancing insulin sensitivity for type 2 diabetes research. Metformin hydrochloride triggers autophagy[1].

Web ID

– HY-110228

Storage Temperature

– 4°C (Powder, sealed storage, away from moisture)

Shipping

– Room Temperature

Applications

– Cancer-Kinase/protease

Molecular Formula

– C4H6D6ClN5

References

– [1]Soraya H, et al. Acute treatment with metformin improves cardiac function following NSC 37745 induced myocardial infarction in rats. Pharmacol Rep. 2012;64(6):1476-84.

CAS Number

– 1185166-01-1

Molecular Weight

– 171.66

Compound Purity

– 98.79

SMILES

– NC(NC(N(C([2H])([2H])[2H])C([2H])([2H])[2H])=N)=N.[H]Cl

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease; Cardiovascular Disease

Solubility

– DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : 50 mg/mL (ultrasonic)

Target

– AMPK;Autophagy;Mitophagy

Isoform

– AMPK

Pathway

– Autophagy;Epigenetics;PI3K/Akt/mTOR

Product type

– Isotope-Labeled Compounds

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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