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MEN 11270
$110 – $520
Products Details
Product Description
– MEN 11270, a cyclic decapeptide, is a B2 kinin receptor antagonist. MEN 11270 bound with high-affinity to the B2 kinin receptor constitutively expressed by WI38 human fibroblasts, inhibiting 3H-bradykinin (BK) with a pKi value of 10.3[1].
Web ID
– HY-103289
Storage Temperature
– -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Shipping
– Blue Ice
Molecular Formula
– C60H90N20O11S
References
– [1]Meini S, et, al. MEN 11270, A novel selective constrained peptide antagonist with high affinity at the human B2 kinin receptor. J Pharmacol Exp Ther. 1999 Jun;289(3):1250-6.
CAS Number
– 235082-52-7
Molecular Weight
– 1299.55
Compound Purity
– 99.15
SMILES
– O=C([C@]1([H])N(C([C@H]2NC([C@@H](NC(CNC([C@H](C[C@H]3O)N(C3)C([C@H](CCC4)N4C([C@H](CCCNC(N)=N)NC([C@H](N)CCCNC(N)=N)=O)=O)=O)=O)=O)CC5=CC=CS5)=O)=O)CC6=CC=CC=C6C1)N7[C@](CCCC8)([H])[C@]8([H])C[C@@]7([H])C(N[C@H](C(NCC2)=O)CCCNC(N)=N)=O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease; Inflammation/Immunology
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Bradykinin Receptor
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
