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Meclofenamic acid (sodium)
$55 – $165
Products Details
Product Description
– Meclofenamic acid (Meclofenamate) sodium is a nonsteroidal anti-inflammatory agent (NSAID) approved for use in arthritis (osteo and rheumatoid), analgesia (mild to moderate pain), dysmenorrhea, and heavy menstrual blood loss (menorrhagia). Meclofenamic acid sodium is a non-selective gap-junction blocker and a highly selective inhibitor of fat mass and obesity-associated (FTO) enzyme inhibitor[1][2][3].
Web ID
– HY-B1320
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C14H10Cl2NNaO2
Citations
– Biomater Adv. 2023 Sep 22, 213634.|Sensor Actuat B-Chem. 2021, 129983.|Theranostics. 2021 Jul 25;11(17):8464-8479.|Biomed Opt Express. 2021 Mar 9.
References
– [1]Conroy MC, et al. Pharmacology, pharmacokinetics, and therapeutic use of meclofenamate sodium. Clin J Pain. 1991;7 Suppl 1:S44-8.|[2]Eleftheriou CG, et al. Meclofenamic acid improves the signal to noise ratio for visual responses produced by ectopicexpression of human rod opsin. Mol Vis. 2017 Jun 16;23:334-345. eCollection 2017.|[3]Huang Y, et al. Meclofenamic acid selectively inhibits FTO demethylation of m6A over ALKBH5. Nucleic Acids Res. 2015 Jan;43(1):373-84.
CAS Number
– 6385-02-0
Molecular Weight
– 318.13
Compound Purity
– 99.86
SMILES
– O=C(O[Na])C1=CC=CC=C1NC2=C(Cl)C=CC(C)=C2Cl
Clinical Information
– Launched
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 125 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)
Target
– Endogenous Metabolite;Gap Junction Protein
Pathway
– Cytoskeleton;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
