MBM-55

SKU T11960-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 299 CAD through 3,984 CAD

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg 500 mg

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Product Description

– MBM-55 is an effective inhibitor of NIMA related kinase 2 (NEK2) with an IC50 of 1 nM. MBM-55 effectively inhibits the proliferation of cancer cells by inducing cell cycle arrest and apoptosis.

Web ID

– T11960

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C28H27FN6O2

References

– Xi JB, et al. Structure-based design and synthesis of imidazo[1,2-a]pyridine derivatives as novel and potent Nek2 inhibitors with in vitro and in vivo antitumor activities. Eur J Med Chem. 2017 Jan 27;126:1083-1106.

CAS Number

– 2083622-09-5

Molecular Weight

– C28H27FN6O2

Compound Purity

– 0.9998

SMILES

– CN(C)CCn1cc(cn1)-c1ccn2c(cnc2c1)-c1ccc(C(N)=O)c(OCc2cccc(F)c2)c1

Target

– Histone Methyltransferase

Pathway

– Chromatin/Epigenetic|||Angiogenesis|||PI3K/Akt/mTOR signaling|||Cell Cycle/Checkpoint|||MAPK|||Cytoskeletal Signaling|||Stem Cells|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

MBM-55

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