Masupirdine free base
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Masupirdine free base

SKU T11948-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 469 CAD through 3,168 CAD

Products Details

Product Description

– Masupirdine free base (SUVN-502 free base) is an orally available 5-HT6 receptor antagonist that crosses the blood-brain barrier, with a Ki value of 2.04 nM for the human 5-HT6 receptor. It is potent and selective, inhibiting multiple targets, and can be used in the study of neurological disorders such as Alzheimer’s disease.

Web ID

– T11948

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H24BrN3O3S

References

– Nirogi R,et al. Discovery and Development of 1-[(2-Bromophenyl)sulfonyl]-5-methoxy-3-[(4-methyl-1-piperazinyl)methyl]-1H-indole Dimesylate Monohydrate (SUVN-502): A Novel, Potent, Selective and Orally Active Serotonin 6 (5-HT6) Receptor Antagonist for Potential Treatment of Alzheimer’s Disease. J Med Chem. 2017 Mar 9;60(5):1843-1859.

CAS Number

– 701205-60-9

Molecular Weight

– C21H24BrN3O3S

Compound Purity

– 0.9965

SMILES

– O=S(=O)(C=1C=CC=CC1Br)N2C=C(C=3C=C(OC)C=CC32)CN4CCN(C)CC4

Target

– Others

Pathway

– Neuroscience|||GPCR/G Protein

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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