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MARK4 inhibitor 1
$157 – $1,950
Products Details
Product Description
– MARK4 inhibitor 1 is a potent and selective microtubule affinity-regulating kinase 4 (MARK4) inhibitor, with an IC50 of 1.54 μM. MARK4 inhibitor 1 inhibits cancer cell proliferation, metastasis and induces apoptosis[1].
Web ID
– HY-114317
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C20H18N6O3
References
– [1]Aneja B, et al. Design and development of Isatin-triazole hydrazones as potential inhibitors of microtubule affinity-regulating kinase 4 for the therapeutic management of cell proliferation and metastasis. Eur J Med Chem. 2019 Feb 1;163:840-852.
CAS Number
– 2271081-58-2
Molecular Weight
– 390.40
Compound Purity
– 98.29
SMILES
– O=C(C1=CN(CC2=CC=C(OC)C=C2)N=N1)N/N=C3C(NC4=C/3C=CC=C4C)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 5 mg/mL (ultrasonic;adjust pH to 2 with HCl)
Target
– AMPK;Apoptosis
Pathway
– Apoptosis;Epigenetics;PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
