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Products Details
Product Description
– MAO-B-IN-26 (Compound IC9) is a MAO-B and acetylcholinesterase inhibitor. MAO-B-IN-26 protects SH?SY5Y cells against Aβ induced cytotoxicity, morphological changes, ROS generation and membrane damage. MAO-B-IN-26 also inhibits Aβ induced autophagy and apoptosis. MAO-B-IN-26 can be used as a neuroprotective agent against Alzheimer’s disease[1].
Web ID
– HY-156348
Shipping
– Room temperature
Molecular Formula
– C17H12BrNO
References
– [1]Sasidharan R, et al. MAO-B Inhibitor (2E)-3-(4-Bromophenyl)-1-(1H-indol-3-yl) prop-2-en-1-one as a Neuroprotective Agent Against Alzheimer’s Disease. Neurochem Res. 2023 Oct 9.
CAS Number
– 38470-71-2
Molecular Weight
– 326.19
SMILES
– O=C(C1=CNC2=C1C=CC=C2)/C=C/C3=CC=C(Br)C=C3
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Autophagy;Cholinesterase (ChE);Monoamine Oxidase
Pathway
– Apoptosis;Autophagy;Neuronal Signaling
Product type
– Reference compound
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