Manzamine A
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Manzamine A

SKU T27977-1 mg Category Brand:

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Product Description

– Manzamine A is a GSK-3 inhibitor and vacuolar ATPase uncoupler found in marine sponges. It inhibits autophagy and tumor growth in cancer models, suppresses foam cell formation in macrophages, prevents growth of gram negative and gram positive bacteria, and decreases tau hyperphosphorylation.

Web ID

– T27977

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C36H44N4O

References

– Pathak RB, Dobson BC, Ghosh N, Ageel KA, Alshawish MR, Saruengkhanphasit R, Coldham I. Synthesis of the tricyclic core of manzamine A. Org Biomol Chem. 2015 Mar 21;13(11):3331-40. doi: 10.1039/c4ob02582b. PubMed PMID: 25647730.

CAS Number

– 104196-68-1

Molecular Weight

– C36H44N4O

SMILES

– [H][C@]12C[C@]34C[N@@]5CC[C@@]3([H])C(=C[C@@](O)(CCC=C/CCCC5)[C@]4([H])N1CCCCC=C2)c1nccc2c3ccccc3[nH]c12 |w:29.32,c:11,17|

Pathway

– Others

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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