Download Files:
Products Details
Product Description
– MALT1-IN-3 (compound 122) is a potent MALT1 protease inhibitor, with an IC50 of 0.06 μM. MALT1-IN-3 has IC50 of 0.14 and 0.13 μM for human IL6/IL10 in OCI-LY3 cells, respectively[1].
Web ID
– HY-143422
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C21H19F3N8O2
References
– [1]Johannes Wilhelmus J Thuring, et al. Pyridine rings containing derivatives as malt1 inhibitors. WO2020208222A1
CAS Number
– 2504229-63-2
Molecular Weight
– 472.42
SMILES
– CO[C@@H](C1CC1)C2=C(C#N)C(C)=NC=C2NC(NC3=CN=C(N4N=CC=N4)C(C(F)(F)F)=C3)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– MALT1
Pathway
– Metabolic Enzyme/Protease;NF-κB
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
