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Products Details
Product Description
– MALT1-IN-11 (Example 151 in reference Patent) is a MALT1 protease inhibitor (IC50 < 10 nM). MALT1-IN-11 inhibits IL10 secretion with an IC50 of 10-100 nM. MALT1-IN-11 can be used for the research of cancer, autoimmune and inflammatory disorders[1].
Web ID
– HY-150232
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C20H16F4N8O
References
– [1]Shulu FENG, et al. Tricyclic compounds useful in the treatment of cancer, autoimmune and inflammatory disoders. Patent. WO2022164789.
CAS Number
– 2812352-99-9
Molecular Weight
– 460.39
SMILES
– CC1(C2=C(C=NC3=CC(F)=NN32)[C@H](C1)C(NC4=CN=C(N5N=CC=N5)C(C(F)(F)F)=C4)=O)C
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– MALT1
Pathway
– Metabolic Enzyme/Protease;NF-κB
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
