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Products Details
Product Description
– Malacidin A is the calcium-dependent antibiotic (CDAs). Malacidin A is highly active against many antibiotic-resistant pathogens, particularly Gram-positive bacteria[1][2].
Web ID
– HY-N10584
Shipping
– Room temperature
Molecular Formula
– C56H88N12O20
References
– [1]Hover BM, et, al. Culture-independent discovery of the malacidins as calcium-dependent antibiotics with activity against multidrug-resistant Gram-positive pathogens. Nat Microbiol. 2018 Apr;3(4):415-422.|[2]Kovalenko N, et, al. A Concise Synthetic Strategy Towards the Novel Calcium-dependent Lipopeptide Antibiotic, Malacidin A and Analogues. Front Chem. 2021 Aug 4;9:687875.
CAS Number
– 2254483-95-7
Molecular Weight
– 1249.37
SMILES
– O=C1N2[C@@](C(NC([C@@H](C(N[C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@@H](C(N[C@H]1C(C)C)=O)[C@H](C)C(O)=O)=O)=O)CC(O)=O)=O)C(O)C(O)=O)=O)CCCCN)=O)C(C)C)=O)NC([C@H]([C@H](C)C(O)=O)NC(/C=C/C=CCCC(C)C)=O)=O)C)=O)([H])C[C@H](C2)C
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Antibiotic;Bacterial
Pathway
– Anti-infection
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
