Mal-PEG8-amide-Val-Ala-(4-NH2)-Exatecan

$350$8,600

Products Details

Product Description

– Mal-PEG8-amide-Val-Ala-(4-NH2)-Exatecan is a conjugate used to synthesis ADC. Mal-PEG8-amide-Val-Ala-(4-NH2)-Exatecan comprises topoisomerase inhibitor derivative with a linker for connecting to a ligand unit (extracted from patent US20200306243A1)[1].

Web ID

– HY-145399

Storage Temperature

– -20°C (Powder, sealed storage, away from moisture and light)

Shipping

– Blue Ice

Applications

– Cancer-programmed cell death

Molecular Formula

– C57H77N7O18

References

– [1]Philip Wilson Howard, et al. Compounds and conjugates thereof. Patent US20200306243A1.

CAS Number

– 2495742-34-0

Molecular Weight

– 1148.26

Compound Purity

– 98.95

SMILES

– O=C1N2C(C(C(C2)=C3C4=C5CCC3)=NC4=CC=C5NC([C@H](C)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN6C(C=CC6=O)=O)=O)=O)=O)=O)=CC7=C1COC([C@]7(O)CC)=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Drug-Linker Conjugates for ADC

Pathway

– Antibody-drug Conjugate/ADC Related

Product type

– ADC Related

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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