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Macitentan (n-butyl analogue)

$180$336

Products Details

Product Description

– Macitentan n-butyl analogue is a n-butyl analogue of Macitentan. Macitentan is an orally active, non-peptide dual endothelin ETA and ETB receptor antagonist for the potential treatment of idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH).

Web ID

– HY-14184A

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C20H21Br2N5O4S

CAS Number

– 556797-16-1

Molecular Weight

– 587.28

Compound Purity

– 99.15

SMILES

– BrC1=CN=C(OCCOC2=C(C3=CC=C(Br)C=C3)C(NS(CCCC)(=O)=O)=NC=N2)N=C1

Clinical Information

– No Development Reported

Research Area

– Cardiovascular Disease; Endocrinology

Solubility

– 10 mM in DMSO

Target

– Endothelin Receptor

Isoform

– ETA;ETB

Pathway

– GPCR/G Protein

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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