Macitentan-d4

SKU T11934-1 mg Category Brand:

Price range: 421 CAD through 1,059 CAD

Products Details

Product Description

– Macitentan-d4 (ACT-064992 D4) is a deuterated substitute for Macitentan and can be used as a dual antagonist of the non-peptides ETA and ETB (endothelin receptor).Macitentan-d4 is less toxic than Macitentan, has a longer half-life, and can be used to study endothelin receptor-mediated diseases.

Web ID

– T11934

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H20Br2N6O4S

References

– Corallo C, et al. Bosentan and macitentan prevent the endothelial-to-mesenchymal transition (EndoMT) in systemic sclerosis: in vitro study. Arthritis Res Ther. 2016 Oct 6;18(1):228.

CAS Number

– 1258428-05-5

Molecular Weight

– C19H20Br2N6O4S

Compound Purity

– 0.9651

SMILES

– N(S(NCCC)(=O)=O)C=1C(=C(OC(C(OC=2N=CC(Br)=CN2)([2H])[2H])([2H])[2H])N=CN1)C3=CC=C(Br)C=C3

Target

– Others

Pathway

– GPCR/G Protein

Product type

– Isotope products

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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